California clash

The NFC West spotlight shifts to Santa Clara as the Rams (6–2) visit the 49ers (6–3). With Brock Purdy not starting—likely only an emergency option—San Francisco’s plan should skew conservative: more runs on early downs, condensed formations, and quick-game throws to stay on schedule while the defense tries to shorten the field. Los Angeles counters with its rhythm passing attack, and Puka Nacua’s upgrade to probable restores the full spacing package that fuels intermediate timing routes and screens. Protection is the hinge: if the Rams keep the pocket clean on first and second down, their tempo can blunt the pass rush and sustain drives.

The market has moved accordingly, flipping from Rams -3.5 on the open to Rams -6 after the quarterback and injury updates. That swing reflects confidence in the visitors’ offensive floor versus uncertainty for the hosts. Levers to watch: red-zone efficiency, turnover margin, and explosives allowed. The total is listed at 49.5.

Pick:
Rams 31
49ers 20